The function of Tripsin Enzyme in Protein Digestion Process

The function of Tripsin Enzyme in Protein Digestion Process

Tripsin is one of the protease enzymes that play an active role in the process of digesting proteins in the body. Enzymes that have the ability to hydrolyze a protein into these smaller sizes are found in the digestive system of vertebrate living beings, for example humans and other mammals. In this article, we will discuss the function of trypsin enzyme in human body, how does this enzyme work in protein digestion process, as well as about other information about this one protease enzyme. Please be listened!

The function of Tripsin Enzyme

In the digestive system, the presence of trypsin is very important. Proteins that enter the body are very large, so it can not be absorbed directly by the lining of the small intestine. This is where the function of trypsin enzyme works. They become a catalyst in the process of protein digestion. They change the size of the protein into smaller through several stages of the process.

The function of Tripsin Enzyme

Production of Tripsin Enzyme

Just like other proteases, trypsin is produced in the pancreas as an inactive tripsinogen protease. Because it is still inactive, to be able to work trypsin must first be stimulated. The stimulation is performed by cholecystokinin. The substance will stimulate zymogen inactive tripsinogen out and into the duodenum.

After being in the duodenum, furthermore the task of enteropeptidase serves to break down trypsinogen into trypsin with proteolytic cleavage. Actually, an automatic catalyst can occur by using trypsinogen as its substrate without the need for other intermediates, but if it continues to occur then the fatal damage to the pancreas may occur. For that reason, this mechanism is necessary to prevent autodegradation of the pancreas.

The function of Tripsin Enzyme in Digestion Process

In simple terms the function of trypsin enzyme is to break the protein into a simpler peptide bond so it can be absorbed by the small intestine and can enter into the bloodstream. Trypsin enzyme in the duodenum works to catalyze and hydrolyze peptide bonds and make proteins into smaller peptides. The peptide product that is formed will be hydrolyzed back by other protease enzymes into amino acids which will then be absorbed by the body and into the bloodstream.

Tripsin Enzyme Mechanism

Basically, the mechanism of action and the properties of trypsin enzyme are similar to other protease enzymes. Amino acids are the smallest arrangement of proteins consisting of three nitrogenous bases that can enter the human circulatory system, so that the protein complex that has been eaten by humans will be transformed into a simple form before entering into the bloodstream. The cells in the body will rearrange the amino acids to be synthesized into a protein back that supports the cell's needs. Together with the enzyme pepsin, trypsin works to help the absorption of protein in food in the stomach.

Benefits And Usage Of Tripsin Enzymes

In some studies, mentioned that in addition to functioning as a catalyst of protein digestion process, trypsin enzyme can also be used as a vaccine meningitis. This enzyme is present in large amounts in the pig's pancreas. Although pig is basically an animal that is forbidden in Islam, but with the existence of today's technology, the enzyme can still be used as a vaccine for the treatment of Muslims, of course, by releasing the haram label it has.

Due to Tripsin Enzyme Deficiency

The most common disorder when we lack trypsin enzyme is malapsorption (absorption disorder). Malapsorsi can be seen from the symptoms that arise such as flatulence, decreased appetite, and also diarrhea. Deficiency of enzymes in the body itself can occur due to several things, one of which is due to the activity of trypsin enzyme.

 Anti Tripsin

Soybean is one of the most commonly consumed nuts commodities by the people, especially the Indonesian people. However, within this one nut actually there are substances that can inhibit the performance of trypsin enzymes. The substance is known as anti-trypsin agent.

As a result of the introduction of anti-trypsin substances into the body, the work of trypsin enzyme in the pancreas will become obstructed, thus causing swelling (hypertrophy) in the pancreas. But the activity of anti trypsin can be removed. How to immersion accompanied by heating or steaming is known to eliminate the content of anti-trypsin in soybeans. Please note that in addition to soy, anti trypsin substances can also be found in almost all types of nuts that we often consume, such as green beans and peanuts.

So a brief review of the function of trypsin enzyme that we can convey. May be useful